Monday, September 22, 2008

23 - immunoglobulins mcqs and faqs


1.
Ig that crosses the placenta ?

Answer: Ig G .

2. Ig present in milk ?

Answer: Ig G and Ig A

3. Ig in seromucinous glands ?

Answer: Ig G and Ig A

4. Ig in primary immune response ?

Answer: Ig M

5. Ig in secondary immune response ?

Answer: Ig G

6. Ig with maximum molecular weight ?

Answer: Ig M

7. Ig with maximum sedimentation rate ?

Answer: Ig M

8. Ig with minimum sedimentation coefficient ?

Answer: Ig G

9. Blood group antibodies belong to which type of immunoglobulins ?

answer: Ig M

10. Rheumatoid factor belongs to which type of immunoglobulins ?

answer: Ig M ( antibody against Fc fragment of Ig G )

11. Immunoglobulin that is heat labile ?

answer: Ig E .

12. Immunoglobulin mediating the prausnitz kustner reaction ?

Answer: Ig E

13. Ig appearing first in life ?

Answer: Ig M

14. homocytotropism is seen in which Ig ?

answer: Ig E .

15. Ig with maximum serum concentration ?

Answer: Ig G

16. Ig with minimum serum concentration ?

Answer: Ig E

17. Ig with longest half life ?

Answer: Ig G

18. Ig with shortest half life ?

Answer: Ig E

19. Ig with maximum synthesis per day ?

Answer: Ig A

20. Ig with minimum synthesis per day ?

Answer: Ig E

21. Ig responsible for hypersensitivity pneumonitis ?

Answer: Ig G

22. binary exposure to an antigen results in sudden increase in ?

answer: Ig G

23. Ig to fix complements via classical pathway ?

Answer: Ig G1 and Ig M

24. Ig to fix complements via alternate pathway ?

Answer: Ig A , Ig D , Ig G4

Sunday, September 7, 2008

22 - morphological changes in myocardial infarction


Evolution of Morphologic Changes in Myocardial Infarction

Time

Gross Features

Light Microscopic Findings

0-½ hr

None

None

½-4hr

None

Usually none; variable waviness of fibers at border

4-12hr

Occasionally dark mottling

Beginning coagulation necrosis; edema; hemorrhage

12-24hr

Dark mottling

Ongoing coagulation necrosis; pyknosis of nuclei; myocyte hypereosinophilia; marginal contraction band necrosis; beginning neutrophilic infiltrate

1-3 days

Mottling with yellow-tan infarct center

Coagulation necrosis, with loss of nuclei and striations; interstitial infiltrate of neutrophils

3-7 days

Hyperemic border; central yellow-tan softening

Beginning disintegration of dead myofibers, with dying neutrophils; early phagocytosis of dead cells by macrophages at infarct border

7-10 days

Maximally yellow-tan and soft, with depressed red-tan margins

Well-developed phagocytosis of dead cells; early formation of fibrovascular granulation tissue at margins

10-14 days

Red-gray depressed infarct borders

Well-established granulation tissue with new blood vessels and collagen deposition

2-8wk

Gray-white scar, progressive from border toward core of infarct

Increased collagen deposition, with decreased cellularity

More

Than

2mon-

ths

Scarring complete

Dense collagenous scar

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