12 - pathology mcqs - 21 to 30

21) Howell Jolly bodies are commonly seen in

a. Megaloblastic Anemia

b. Sickle cell anemia

c. Iron deficiency anemia

d. After splenectomy

Answer : d) After Splenectomy

Reference: Harrison 15^th Edition Chapter 116

22) Most specifice antibody for SLE

a. Anti dsDNA

b. SS-A (Ro)

c. SS-B (La)

d. Anticentromere

Answer : a) Anti ds DNA

Reference: Harrison 16th Edition Pages 317, 1979 and Robbins 7th Edition Page 229

23) All of the following malignancies are associated with HIV except

a. Kaposi’s sarcoma

b. Primary Brain lymphoma

c. primary effusion lymphoma

d. Astrocytoma

Answer : d) Astrocytoma

Reference: Robbins 7^th Edition Page 255

24) Burkitts’ lymphoma chromosome

a. t(8,14)

b. t(9,22)

c. t(1,14)

d. t(2,16)

Answer : A) T(8,14)

Reference: Robbins 7^th Edition Page 671

25) Philadelphia chromosome seen in

a. CML

b. CLL

c. AML

d. ALL

Answer : A) CML

Reference: Robbins 7^th Edition Page 697

26) MacCallum’s plaques are seen in

a. Right Atrium

b. Left Atrium

c. Right Ventricle

d. Left Ventricle

Answer : b) Left Atrium

Reference: Robbins 7^th Edition Page

27) Libman Sack’s endocarditis seen in

a. SLE

b. Rheumatic Fever

c. Both

d. None

Answer : a) SLE

Reference: Robbins 7^th Edition Page 597

28) Irreversible cell injury is seen in

a. Apoptosis

b. Hypertrophy

c. Hyaline change

d. Fatty change

Answer : Apoptosis

Reference: Robbins 7^th Edition Page 26

29) Apoptosis is

a. Programmed cell death

b. Increase in number of cells

c. Increase in bulk of cells

d. None of the above

Answer : a) Programmed cell death

Reference: Robbins 7^th Edition Page 26

30) Hypertrophy of muscle is due to

a. Increase in number of mitochodnria

b. Increase in size of mitochondria

c. Decrease in number of mitochodria

d. Abnormal shape of mitochondria

Answer : a) Increase in number of mitochondria

Reference: Robbins 7^th Edition Page 33